Asmoro Lelono

Biology Department, Faculty of Mathematics and Natural Sciences, University of Jember, Indonesia

Rizky Surya

Biology Department, Faculty of Mathematics and Natural Sciences, University of Jember, Indonesia

DOI: https://doi.org/10.19184/lsb.v1i2.43625

ABSTRACT 

Salmonella is a gram-negative bacteria commonly found in poultry-based products such as eggs and meat, which can affect quality and human health. The presence of these bacteria in poultry management can be traced to feed, water, substrate, and interactions with the environment. This study aims to investigate the immune system of the avian through injection of Salmonella typhimurium colonies at the age of the immune system begins to be produced independently. Salmonella culture at a density of 10-8 and 10-12 was injected into the digestive tract, and the increase in body temperature was measured immediately after injection. Two weeks later, an analysis of leukocyte differentiation was carried out. We found that Salmonella injection affected body temperature and the rate of body mass increased in all treatments and sex. This indicates that the immune system was activated even though the leukocyte differentiation indicators did not show any significant results. Chicks at the age of one month can show an immune response to bacterial infections through self-defense mechanisms. Further research needs to be carried out to understand whether leukocyte differentiation stimulates leukocyte variation with age.

Keywords: immune system, avian, body temperature, Salmonella typhimurium.