Ika Iffah Ilmiah

Science Education Department, Faculty of Teacher Training and Education, University of Jember, Jember, Indonesia.

Young Writers and Researchers Organization, MAN 2 Jember, Jember, Indonesia

Farah Fakhirah Mufidi

Young Writers and Researchers Organization, MAN 2 Jember, Jember, Indonesia

Excel Taruna Reksa Perkasa

Young Writers and Researchers Organization, MAN 2 Jember, Jember, Indonesia

Chleovia Dzaky Putri Isdarmanto

Young Writers and Researchers Organization, MAN 2 Jember, Jember, Indonesia

Muhammad Husein Shodiq

Department of Physics, Faculty of Mathematics and Natural Sciences, University of Jember, Jember, Indonesia

Abdulloh Hasan Shodiq

Department of Physics, Faculty of Mathematics and Natural Sciences, University of Jember, Jember, Indonesia

Abdillah Maulana Farhan

Laboratory of Botany, Department of Biology, Faculty of Mathematics and Natural Sciences, University of Jember, Jember, Indonesia

DOI: https://doi.org/10.19184/lsb.v3i1.53645

ABSTRACT 

Ginger (Zingiber officinale Roscoe), a widely used rhizomatous species of the family Zingiberaceae, possesses extensive medicinal value owing to its diverse phytochemical composition. This study aimed to characterize the bioactive constituents of locally grown ginger rhizomes using Gas Chromatography–Mass Spectrometry (GC–MS) to elucidate their potential pharmacological activities. GC–MS analysis enabled the detection of volatile and semi-volatile compounds based on retention time and molecular ion fragmentation patterns, providing a comprehensive chemical profile of the extract. A total of 39 compounds were identified, of which 14 exhibited relative abundances exceeding 3%. Major constituents included sesquiterpenes and phenolic derivatives known for their antioxidant, antimicrobial, anti-inflammatory, and anticancer properties. The presence of these bioactive metabolites confirms the therapeutic potential of Z. officinale as a natural source of bioactive agents and supports its continued exploration for pharmaceutical and nutraceutical applications.

Keywords: bioactive compounds, GC-MS, natural medicine, rhizome, Zingiber officinale.